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Mirtazapine Tablets 30mg

作者:admin   時間:2018-11-21

  [drug name]

  General name: Mirtazapine Tablets

  Trade name: Mirtazapine Tablets 30mg*10

  Pinyin full code: PaiDiSheng MiDanPingPian 30mg*10Pian

  [main ingredients]

  The main ingredient of this product is mirtazapine. The chemical name of mirtazapine is: 1,2,3,4,10,14b-hexahydro-2-methyl.pttzino [2,l-a], pyridine [2,3-c] [chemical formula of 21 phenylaza-coated mirtazapine: molecular weight of C17H19N3-meter azapine: 265.36


  This product is a film coated tablet, which is white or white after removing film coating.

  Indications / indications


  [specification type]

  30mg*10 film (pads)

  [usage and dosage]

  Oral administration can be swallowed with water and not chewed.

  For adults, the initial dose is 15 mg (1/2 tablets) once a day, and then gradually increased to achieve the best therapeutic effect. The effective oral dose is usually 15-45 mg (1/2 tablets-1.5 tablets) per day.

  In patients with liver and kidney impairment, the clearance ability of mirtazapine decreases. Therefore, attention should be paid to the use of mirtazapine in these patients. The half-life of mirtazapine is 20-40 hours, so the medication can be taken once a day, and the effect is better before going to bed. Can also be divided into clothes, sooner or later each time.

  The patient should continue taking the medicine. It is best to stop the medicine after the symptoms disappear completely after 4-6 months. The appropriate dose will have a significant effect within 2-4 weeks. If the effect is not obvious, the dosage can be increased until the maximum dose. If there is no significant effect within 2-4 weeks after the dosage, the drug should be stopped immediately.

  [adverse reactions]

  1. Patients with depression often show a series of disease-related phenomena, so it is sometimes difficult to determine whether a phenomenon is the manifestation of the disease itself or the adverse reactions after taking mirtazapine. The common side effects of mirtazapine were:

  1) increased appetite and weight gain;

  2) Fatigue and sedation usually occur within one week after taking the medicine (note that the reduction of dose at this time will not alleviate this adverse reaction, but will affect the treatment effect of depression);

  2. in a few cases, the following symptoms may occur:

  1) (postural) hypotension;

  2) mania;

  3) convulsive seizures, tremors and muscle spasms.

  4) edema and associated weight gain;

  5) Acute myelosuppression (agranulocytosis, aplastic anemia, thrombocytopenia, various types of cell reduction) (see the use of precautions);

  6) elevated serum aminotransferase.

  7) drug rash.


  Mirtazapine allergies are prohibited.


  1. Most antidepressants have bone marrow depression, manifested as granulocytopenia and granulocytopenia. The symptoms mostly occur within 4-6 weeks after the use of antidepressants, and most of them can return to normal after withdrawal. In the clinical study of mirtazapine, this reversible leucocytosis has been found in very few patients, so doctors should pay attention to the treatment process, such as patients with fever, sore throat, stomach and other symptoms of infection should stop using drugs, and make peripheral blood examination.

  2. patients with the following diseases should pay attention to the dosage and check them regularly.

  (1) Epilepsy and organic brain tissue syndrome: Clinical experience has shown that mirtazapine rarely causes adverse reactions.

  (2) liver and kidney insufficiency.

  (3) cardiovascular disease, such as conduction block, angina pectoris and recent onset myocardial infarction. Routine precautions should be taken and caution should be taken with other drugs.

  (4) hypotension.

  3. as with other antidepressants, the following patients should pay attention to the use of rice nitrogen.

  (1) dysuria such as prostatic hypertrophy. Although mirtazapine has only a weak anticholinergic activity, it rarely causes adverse reactions when used.

  (2) increased intraocular pressure in acute angle glaucoma. (similarly, mirtazapine has only a weak anticholinergic activity, which rarely occurs).

  (3) diabetic patients.

  4. if the patient develops jaundice, discontinue treatment immediately.

  5. in addition, as with other antidepressants, the following situations should also be noted:

  (1) When antidepressants are used to treat patients with schizophrenia and other psychiatric and venereal diseases, the symptoms of psychosis may deteriorate and the false thoughts may increase.

  (2) when mania depression is used, it may lead to mania.

  (3) Considering that patients may commit suicide, especially in the early stage of treatment, the prescription dose of mirtazapine tablets should be limited.

  (4) Although antidepressants are not addictive, they may cause nausea, headache and discomfort after a sudden withdrawal of drugs for a long time.

  6. Older people are usually more sensitive to adverse reactions of antidepressants, but in clinical trials of mirtazapine, no more adverse reactions were observed in elderly patients. However, the clinical experience is limited.

  Taking this product may affect attention and responsiveness. Therefore, it should be avoided to engage in operational activities requiring higher attention and responsiveness, such as driving.

  [drug interaction]

  1. Mirtazapine may aggravate the inhibitory effect of alcohol on the central nervous system, so alcohol should not be consumed during treatment. 2. it should avoid simultaneous use of monoamine oxidase or the time interval between the two uses is less than 14 days. 3. Mirtazapine can aggravate the sedative effect of benzodiazepines. Therefore, attention should be paid to the simultaneous use of mirtazapine and benzodiazepines.

  [child medication]

  It is not clear yet.

  [medication for elderly patients]

  Recommended dosage